BDBM312609 US9604998, Example 15::US9604998, Example 37

SMILES COc1cc(C(O)CN2CCN3C[C@H](OC[C@@H]3C2)c2ccc3C(=O)OCc3c2C)c(F)cc1C#N

InChI Key InChIKey=KDBUILMPSQLILM-DQNHKJGCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312609   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312609(US9604998, Example 15 | US9604998, Example 37)
Affinity DataIC50:  110nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312609(US9604998, Example 15 | US9604998, Example 37)
Affinity DataIC50:  290nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent