BDBM312646 US9604998, Example 46
SMILES C[C@@H]1Cc2cc(ccc2C(=O)O1)C(O)CN1CCN2C[C@H](OC[C@@H]2C1)c1ccc2C(=O)OCc2c1C
InChI Key InChIKey=HGKYZNAKKJCVCB-KLMDZHMFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312646
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 110nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair