BDBM312717 (5S)-5-benzyloxy-1-[4-[2-[(3R)- 3-hydroxy-1-methyl-2- oxo-pyrrolidin-3-yl]ethynyl]- 2-pyridyl]-6,6-dimethyl- 5,7-dihydro-4H-indazole-3- carboxamide::US9605005, Example 7

SMILES CN1CC[C@@](O)(C#Cc2ccnc(c2)-n2nc(C(N)=O)c3C[C@H](OCc4ccccc4)C(C)(C)Cc23)C1=O

InChI Key InChIKey=NDMYTORHXSWZLR-IADCTJSHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312717   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312717((5S)-5-benzyloxy-1-[4-[2-[(3R)- 3-hydroxy-1-methyl...)
Affinity DataKi:  45.5nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent