BDBM312729 5-acetyl-1-[3-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-pyrroli- din-3-yl]ethynyl]phenyl]- 6,7-dihydro-4H-pyrazolo[4,3- c]pyridine-3-carboxamide::US9605005, Example 19

SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3CN(CCc23)C(C)=O)C1=O

InChI Key InChIKey=VTVFVCAHYRFAGQ-QFIPXVFZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312729   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312729(5-acetyl-1-[3-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-...)
Affinity DataKi:  10.2nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent