BDBM312752 5-(cyanomethyl)-1-[3-[2-[(3R)- 3-hydroxy-1-methyl-2- oxo-pyrrolidin-3-yl]ethynyl] phenyl]indazole-3-carboxamide::US9605005, Example 41

SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3cc(CC#N)ccc23)C1=O

InChI Key InChIKey=QIFKZTJNASZDEG-QHCPKHFHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312752   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312752(5-(cyanomethyl)-1-[3-[2-[(3R)- 3-hydroxy-1-methyl-...)
Affinity DataKi:  0.320nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent