BDBM312791 1-[4-[(3R)-3-hydroxy-3-(5- methylisoxazol-3-yl)but-1- ynyl]-2-pyridyl]-5-methyl- pyrazole-3-carboxamide::US9605005, Example 80

SMILES Cc1cc(no1)[C@](C)(O)C#Cc1ccnc(c1)-n1nc(cc1C)C(N)=O

InChI Key InChIKey=OUEKIUOANBSUEO-GOSISDBHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312791   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312791(1-[4-[(3R)-3-hydroxy-3-(5- methylisoxazol-3-yl)but...)
Affinity DataKi:  84.5nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent