BDBM312823 5-[1-(2-hydroxyethyl)pyrazol- 4-yl]-1-[3-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-pyrroli- din-3-yl]ethynyl]phenyl] indazole-3-carboxamide::US9605005, Example 113

SMILES CN1CC[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3cc(ccc23)-c2cnn(CCO)c2)C1=O

InChI Key InChIKey=DPOZIEFFQUVCRM-SANMLTNESA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312823   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM312823(5-[1-(2-hydroxyethyl)pyrazol- 4-yl]-1-[3-[2-[(3R)-...)
Affinity DataKi:  0.0700nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent