BDBM312965 3′-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]spiro[cyclopropane-1,7′-pyrrolo[2,3-e][1,2,4]triazin]-6′(5′H)-one::US9605008, 26

SMILES Cc1ccc2c(nn(Cc3ccc(C)c(F)c3F)c2n1)-c1nnc2c(NC(=O)C22CC2)n1

InChI Key InChIKey=BKDAZJWQUSLKLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312965   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312965(3′-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl...)
Affinity DataIC50:  4nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent