BDBM313020 N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-1-methyl-1H-1,2,3-triazole-4-carboxamide::US10166216, Compound 30::US9605007, Example 76

SMILES COc1cccc(n1)-n1nc(Nc2ccc(OCCN3CCCC3)cc2)nc1N

InChI Key InChIKey=OZYRAKXEBKZWKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313020   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM313020(N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetra...)
Affinity DataIC50:  2.81E+4nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM313020(N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetra...)
Affinity DataIC50:  5.50E+3nMAssay Description:The resulting chemiluminescence was read with a Luminomitor within 10 minutes to minimize changes in signal intensity. After reading the chemilumines...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent