BDBM313213 1-(4-cyclopropylphenyl)-N-(1-ethyl-8-fluoro-2-oxo-3,4-dihydroquinolin-6-yl)methanesulfonamide::US10167261, Compound 1.213

SMILES CCN1C(=O)CCc2cc(NS(=O)(=O)Cc3ccc(cc3)C3CC3)cc(F)c12

InChI Key InChIKey=YROABANQOSHQJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313213   

TargetAbscisic acid receptor PYL2/Protein phosphatase 2C 16(Arabidopsis thaliana (Mouse-ear cress))
University Of California

US Patent
LigandPNGBDBM313213(1-(4-cyclopropylphenyl)-N-(1-ethyl-8-fluoro-2-oxo-...)
Affinity DataIC50:  244nMAssay Description:HAB1 and PYL proteins were expressed and purified as described in Park et al. ((2009) Science 324(5930):1068-1071), with minor modifications. To obta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAbscisic acid receptor PYL1/Protein phosphatase 2C 16(Arabidopsis thaliana (Mouse-ear cress))
University Of California

US Patent
LigandPNGBDBM313213(1-(4-cyclopropylphenyl)-N-(1-ethyl-8-fluoro-2-oxo-...)
Affinity DataIC50:  21nMAssay Description:HAB1 and PYL proteins were expressed and purified as described in Park et al. ((2009) Science 324(5930):1068-1071), with minor modifications. To obta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent