BDBM313412 US10167270, Example 92

SMILES CC(CNc1nc(nc2ccccc12)-c1cccnc1)Oc1ccccc1

InChI Key InChIKey=RKKRWKMFEZFLPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313412   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313412(US10167270, Example 92)
Affinity DataIC50:  4.24E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313412(US10167270, Example 92)
Affinity DataIC50:  5.01E+3nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent