BDBM31376 CHEMBL433422::terephthalamide scaffold, 24

SMILES COC(=O)[C@@H](NC(=O)c1ccc(cc1OC(C)C)C(=O)N(C(C)C)C(C)C)C(C)C

InChI Key InChIKey=BGSQJLBMFYVHEF-FQEVSTJZSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31376   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM31376(CHEMBL433422 | terephthalamide scaffold, 24)
Affinity DataKi:  5.85E+3nMAssay Description:Binding affinity for Bcl-xL was assessed by a fluorescence polarizationassay using a fluorescently labeled 16-mer Bak-peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM31376(CHEMBL433422 | terephthalamide scaffold, 24)
Affinity DataKi:  5.85E+3nM ΔG°:  -7.13kcal/molepH: 7.4 T: 2°CAssay Description:Fluorescence polarization experiments were conducted on a Photon Technology International instrument using a 0.3 cm path length cuvette. Spectra were...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed