BDBM313949 US10167296, Example 3.01

SMILES C[C@@H](Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)c(OCC3CC3)c(C)c12)C(F)(F)F

InChI Key InChIKey=WZDDWQHGNFSHRU-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313949   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM313949(US10167296, Example 3.01)
Affinity DataIC50:  180nMAssay Description:The Z′-LYTEŽ biochemical assay employs a fluorescence-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM313949(US10167296, Example 3.01)
Affinity DataIC50:  3.30nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent