BDBM314763 US9611265, Ex. 3-50-1

SMILES COc1cc(ccc1OCc1ccc(cc1)C(F)(F)F)C(C)n1c(N)nc2cc(cnc12)-c1cnn(CCO)c1

InChI Key InChIKey=GVDDEBQJCYQLKV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 314763   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM314763(US9611265, Ex. 3-50-1)
Affinity DataIC50:  0.400nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM314763(US9611265, Ex. 3-50-1)
Affinity DataIC50:  19nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM314763(US9611265, Ex. 3-50-1)
Affinity DataIC50:  0.600nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent