BDBM31491 substituted biphenyl derivative, 36ae

SMILES CC(C)CNC(=O)c1ccc(c(c1)C(O)=O)-c1ccc(cc1C(=O)Nc1ccc(cc1)C(N)=N)-c1cccn1C

InChI Key InChIKey=SYSCAMXJUQSOPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31491   

TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31491(substituted biphenyl derivative, 36ae)
Affinity DataIC50:  76nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31491(substituted biphenyl derivative, 36ae)
Affinity DataIC50:  50nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31491(substituted biphenyl derivative, 36ae)
Affinity DataIC50:  8.69E+4nMT: 2°CAssay Description:Thrombin assay reactions were performed in a reaction mixture containing thrombin, and test compounds were added at varied concentrations. The reacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Biocryst Pharmaceuticals

LigandPNGBDBM31491(substituted biphenyl derivative, 36ae)
Affinity DataIC50:  410nMT: 2°CAssay Description:Trypsin assay reactions were performed in a mixture containing trypsin, and test compounds were added at varied concentrations. The reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed