BDBM315308 3-{1-[2-(3,4-Dichloro- phenyl)-5-methyl-1H- imidazol-4-ylmethyl]- piperidin-4-yl}-3,4- dihydro-1H-quinazolin- 2-one::US10172843, Example 42

SMILES Cc1[nH]c(nc1CN1CCC(CC1)N1Cc2ccccc2NC1=O)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WJUPPLHHQDUYQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315308   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315308(3-{1-[2-(3,4-Dichloro- phenyl)-5-methyl-1H- imidaz...)
Affinity DataIC50:  287nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent