BDBM315337 3-{1-[1,5-Dimethyl-2-(4- trifluoromethyl-phenyl)- 1H-imidazol-4- ylmethyl]-piperidin-4- yl}-3,4-dihydro-1H- quinazolin-2-on::US10172843, Example 71

SMILES Cc1c(CN2CCC(CC2)N2Cc3ccccc3NC2=O)nc(-c2ccc(cc2)C(F)(F)F)n1C

InChI Key InChIKey=IWQQGYBLSHZHJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315337   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315337(3-{1-[1,5-Dimethyl-2-(4- trifluoromethyl-phenyl)- ...)
Affinity DataIC50:  84nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent