BDBM315343 3-{1-[5-Methyl-2-(4- trifluoromethanesulfonyl- phenyl)-1H-imidazol-4- ylmethyl]-piperidin-4- yl}-1H-pyrrolo[3,2- c]pyridine::US10172843, Example 77

SMILES Cc1[nH]c(nc1CN1CCC(CC1)c1c[nH]c2ccncc12)-c1ccc(cc1)S(=O)(=O)C(F)(F)F

InChI Key InChIKey=XBNPSQAUTIABIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315343   

TargetCathepsin S(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM315343(3-{1-[5-Methyl-2-(4- trifluoromethanesulfonyl- phe...)
Affinity DataIC50:  155nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent