BDBM31587 oxadiazole derivative, 20x
SMILES COc1ccc(cc1)-n1cnc2ccc(cc12)-c1nnc(SCc2cccc(c2)C#N)o1
InChI Key InChIKey=XUEHEOHRTKKVET-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 31587
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Takeda Pharmaceutical
Takeda Pharmaceutical
Affinity DataIC50: 4.60E+3nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Assays for serine/threonine kinases using radiolabeled [gamma-33P] ATP (GE Healthcare, Piscataway, NJ) were performed in 96 well plates. Prior to the...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Human p35/ cyclin dependent kinase 5 (CDK5) was purchased from Millipore Corp. (Bedford, MA), which was expressed as N-terminal GST fusion protein us...More data for this Ligand-Target Pair