BDBM315932 US10172859, Example 356::US11065253, Example 356::US9732094, Example 356::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]pyrrolo[1,2-a]- pyrazin-1-ylmethanol1H NMR (500 MHz, DMSO-d6) ppm = 9.10 (s,1H), 8.20 (dd, J = 4.8, 1.0, 1H), 7.79-7.72 (m, 3H),7.53-7.45 (m, 3H), 7.40-7.34 (m, 1H), 7.20 (d,J = 2.1, 1H), 7.02 (dt, J = 4.1, 1.2, 1H), 6.87 (dd,J = 4.1, 2.5, 1H), 6.33 (d, J = 4.9, 1H), 6.06 (d,J = 4.8, 1H), 3.82-3.76 (m, 4H), 3.48-3.42 (m,4H).
SMILES OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12
InChI Key InChIKey=KEDFGJHVFDJAQW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315932
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataKi: <1.00E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataKi: <1.00E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair