BDBM316480 2-{[(3R,6R)-1-{[6-Methoxy-2-(2H-1,2,3-triazol-2-yl)pyridin-3-yl]carbonyl}-6-methylpiperidin-3-yl]sulfanyl}pyridine-4-carbonitrile ::US9617246, 14

SMILES COc1ccc(C(=O)N2C[C@@H](CC[C@H]2C)Sc2cc(ccn2)C#N)c(n1)-n1nccn1

InChI Key InChIKey=BJFVKXHRNWFXOO-GDBMZVCRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316480   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316480(2-{[(3R,6R)-1-{[6-Methoxy-2-(2H-1,2,3-triazol-2-yl...)
Affinity DataIC50:  1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316480(2-{[(3R,6R)-1-{[6-Methoxy-2-(2H-1,2,3-triazol-2-yl...)
Affinity DataIC50:  149nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent