BDBM316494 2-{[(3R,6R)-1-(biphenyl-2-ylcarbonyl)-6- methylpiperidin-3-yl]sulfanyl}pyridine-4- carbonitrile::US9617246, 28

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-c1ccccc1)Sc1cc(ccn1)C#N

InChI Key InChIKey=MVLJMQQXIGILAK-WIYYLYMNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316494   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316494(2-{[(3R,6R)-1-(biphenyl-2-ylcarbonyl)-6- methylpip...)
Affinity DataIC50:  279nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316494(2-{[(3R,6R)-1-(biphenyl-2-ylcarbonyl)-6- methylpip...)
Affinity DataIC50:  16.7nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent