BDBM316742 2-[(1-acryloylpiperidin-4-yl)amino]-N-{[(3R)-1-hydroxy-3-methylcyclopentyl]methyl}-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide::US11111242, Example 239::US9617258, Example 239
SMILES C[C@@H]1CCC(O)(CNC(=O)c2c[nH]c3ncc(NC4CCN(CC4)C(=O)C=C)nc23)C1
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 316742
Affinity DataIC50: 0.5nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair
Affinity DataIC50: 38.1nMAssay Description:JAK Caliper Enzyme Assay at 1 mM ATP: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half l...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:JAK Caliper Enzyme Assay at 4 μM: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half ...More data for this Ligand-Target Pair
Affinity DataIC50: 38.1nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair