BDBM317148 3-Methyl-6-(2-(1-methyl-5-(pyrrolidin-1-yl)-1H-1,2,4-triazol-3-yl)ethyl)-2-(trifluoromethyl)imidazo[1,2-b]pyridazine::US9617271, 6
SMILES Cc1c(nc2ccc(CCc3nc(N4CCCC4)n(C)n3)nn12)C(F)(F)F
InChI Key InChIKey=VGWQQXTVMNQBRU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 317148
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 19nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair