BDBM317148 3-Methyl-6-(2-(1-methyl-5-(pyrrolidin-1-yl)-1H-1,2,4-triazol-3-yl)ethyl)-2-(trifluoromethyl)imidazo[1,2-b]pyridazine::US9617271, 6

SMILES Cc1c(nc2ccc(CCc3nc(N4CCCC4)n(C)n3)nn12)C(F)(F)F

InChI Key InChIKey=VGWQQXTVMNQBRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317148   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM317148(3-Methyl-6-(2-(1-methyl-5-(pyrrolidin-1-yl)-1H-1,2...)
Affinity DataIC50:  19nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent