BDBM317151 (E)-8-methoxy-3-methyl-6-(2-(1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)vinyl)-2-(trifluoromethyl)imidazo[1,2-b]pyridazine::US9617271, 9
SMILES COc1cc(\C=C\c2nc(nn2C)N2CCCC2)nn2c(C)c(nc12)C(F)(F)F
InChI Key InChIKey=LLOPFJKSYHFXLU-VOTSOKGWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 317151
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair