BDBM317222 US9617272, Compound 68::US9981973, Compound 68

SMILES OC(CC1c2ccccc2-c2cnnn12)C1CCC(F)(F)CC1

InChI Key InChIKey=LQHHDYXPADTYTB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 317222   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317222(US9617272, Compound 68 | US9981973, Compound 68)
Affinity DataIC50:  5.50E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317222(US9617272, Compound 68 | US9981973, Compound 68)
Affinity DataIC50:  1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317222(US9617272, Compound 68 | US9981973, Compound 68)
Affinity DataIC50:  1.00E+4nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM317222(US9617272, Compound 68 | US9981973, Compound 68)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of TDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent