BDBM317454 US9617250, Example 233 of D1
SMILES CCc1cc(cc(C)c1OC[C@@H](O)CNC(=O)CO)-c1noc(n1)-c1cc(C)nc(c1)C1CCCC1
InChI Key InChIKey=UUIZGTQHTWIYDY-QFIPXVFZSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 317454
Affinity DataEC50: 0.200nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Actelion Pharmaceuticals
Curated by ChEMBL
Actelion Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at human recombinant S1P1 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Actelion Pharmaceuticals
Curated by ChEMBL
Actelion Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair