BDBM317454 US9617250, Example 233 of D1

SMILES CCc1cc(cc(C)c1OC[C@@H](O)CNC(=O)CO)-c1noc(n1)-c1cc(C)nc(c1)C1CCCC1

InChI Key InChIKey=UUIZGTQHTWIYDY-QFIPXVFZSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 317454   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM317454(US9617250, Example 233 of D1)
Affinity DataEC50:  0.200nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM317454(US9617250, Example 233 of D1)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human recombinant S1P3 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM317454(US9617250, Example 233 of D1)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human recombinant S1P1 receptor expressed in CHO cells incubated for 30 mins prior to [35S]-GTPgammaS addition measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM317454(US9617250, Example 233 of D1)
Affinity DataEC50:  47nMAssay Description:GTPγS binding assays are performed in 96 well microtiter plates (Nunc, 442587) in a final volume of 200 μl, using membrane preparations of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent