BDBM317468 4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6-yl)-7H- pyrrolo[2,3-d]pyrimidin-2- ylamino)-N-(2-hydroxyethyl)-3- methoxybenzamide::US9623028, Compound 101

SMILES COc1cc(ccc1Nc1nc(OC2CCCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NCCO

InChI Key InChIKey=DUZMKFLMNMTYDM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 317468   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317468(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)
Affinity DataIC50:  2.13nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317468(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)
Affinity DataIC50:  501nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317468(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)
Affinity DataIC50:  3.38nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317468(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)
Affinity DataIC50:  99.8nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent