BDBM317471 (S)-3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4- (tetrahydrofuran-3-yloxy)-7H- pyrrolo[2,3-d]pyrimidin-2- ylamino)benzamide::US9623028, Compound 134

SMILES CNC(=O)c1ccc(Nc2nc(O[C@H]3CCOC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317471   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317471((S)-3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazo...)
Affinity DataIC50:  1.68nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317471((S)-3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazo...)
Affinity DataIC50:  2.27nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317471((S)-3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazo...)
Affinity DataIC50:  130nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent