BDBM317540 6-chloro-3-[(1S)-1-({2-oxo-2H,3H-[1,3]oxazolo[4,5-d]pyrimidin-5-yl}amino)ethyl]-1,2-dihydroquinolin-2-one::US9624175, Compound I-56

SMILES C[C@H](Nc1ncc2oc(=O)[nH]c2n1)c1cc2cc(Cl)ccc2[nH]c1=O

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317540   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [1-390,401-414,R132C](Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM317540(6-chloro-3-[(1S)-1-({2-oxo-2H,3H-[1,3]oxazolo[4,5-...)
Affinity DataIC50:  550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM317540(6-chloro-3-[(1S)-1-({2-oxo-2H,3H-[1,3]oxazolo[4,5-...)
Affinity DataIC50: <100nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent