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BDBM317551 (s)-3-(4-(diisobutylamino)-3-(3-(pyrimidin-5-yl)ureido)phenyl)butanoic acid::US9624188, 38

SMILES: CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cncnc1)[C@@H](C)CC(O)=O

InChI Key: InChIKey=LJCAFMSKDUEZRV-KRWDZBQOSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317551   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (human))
BDBM317551
PNG
((s)-3-(4-(diisobutylamino)-3-(3-(pyrimidin-5-yl)ur...)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cncnc1)[C@@H](C)CC(O)=O
Show InChI InChI=1S/C23H33N5O3/c1-15(2)12-28(13-16(3)4)21-7-6-18(17(5)8-22(29)30)9-20(21)27-23(31)26-19-10-24-14-25-11-19/h6-7,9-11,14-17H,8,12-13H2,1-5H3,(H,29,30)(H2,26,27,31)/t17-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 29n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9624188 (2017)

More data for this
Ligand-Target Pair