BDBM317575 N-((3R,6R)-1-(2-(2H-1,2,3-Triazol-2-yl)benzoyl)-6-methylpiperidin-3-yl)-N-(4-cyanopyridin-2-yl)acetamide::US9624197, 15

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)N(C(C)=O)c1cc(ccn1)C#N

InChI Key InChIKey=RGJDOWXDEVFFCO-VQIMIIECSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317575   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM317575(N-((3R,6R)-1-(2-(2H-1,2,3-Triazol-2-yl)benzoyl)-6-...)
Affinity DataIC50:  1.00E+4nMAssay Description:FLIPR Ca2+ Flux Assay- (Okumura et al., Biochem. Biophys. Res. Comm. 280:976-981, 2001). In a typical experiment the OX1 and OX2 receptor antagonisti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM317575(N-((3R,6R)-1-(2-(2H-1,2,3-Triazol-2-yl)benzoyl)-6-...)
Affinity DataIC50:  1.78E+3nMAssay Description:FLIPR Ca2+ Flux Assay- (Okumura et al., Biochem. Biophys. Res. Comm. 280:976-981, 2001). In a typical experiment the OX1 and OX2 receptor antagonisti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent