BDBM317576 [4-(3,4-Dihydroisoquinolin-2-(1H)-yl)piperidin-1-yl]{6-[(2-methoxyethyl)amino]pyridin-3-yl}-methanone::US9624198, 1

SMILES COCCNc1ccc(cn1)C(=O)N1CCC(CC1)N1CCc2ccccc2C1

InChI Key InChIKey=LUHIUDADEUMEFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317576   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317576( [4-(3,4-Dihydroisoquinolin-2-(1H)-yl)piperidin-1-...)
Affinity DataIC50:  22nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent