BDBM317625 3-(4-{5- Amino-4-[4- (1H-pyrazol-4- yl)-1H-indole- 2-carbonyl]- pyrazol-1-yl}- 3-methyl- phenoxy)- benzonitrile::US10640491, Compound 14::US11104668, Compound 14::US9624201, Compound 14
SMILES Cc1cc(Oc2cccc(c2)C#N)ccc1-n1ncc(C(=O)c2cc3c(cccc3[nH]2)-c2cn[nH]c2)c1N
InChI Key InChIKey=GWSLLIVSORPVSL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 317625
Affinity DataIC50: 8.38nMAssay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of Btk, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 8.38nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 8.38nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair