BDBM317634 US9624205, 3

SMILES CCC(C)n1cc(C)c2c(cc(cc12)-c1ccc(nc1)N1CCNCC1)C(=O)NCc1c(C)n(C)nc1OC

InChI Key InChIKey=RBRSCFOTNWAFGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317634   

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM317634(US9624205, 3)
Affinity DataIC50:  548nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM317634(US9624205, 3)
Affinity DataIC50:  4.33E+3nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent