BDBM317669 US11337976, Compound P-0040::US20230277534, Compound P-0040::US9624213, Compound P-0040

SMILES CCCN(C)S(=O)(=O)Nc1cccc(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(OC)nc2)c1F

InChI Key InChIKey=ZRKPGRIKGPMYRD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317669   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317669(US11337976, Compound P-0040 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317669(US11337976, Compound P-0040 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:The biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, where inhibit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM317669(US11337976, Compound P-0040 | US20230277534, Compo...)
Affinity DataIC50: <100nMAssay Description:For example, the biochemical activity IC50 values are determined with respect to inhibition of B-Raf V600E kinase activity or p-Erk kinase activity, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent