BDBM31773 ECONAZOLE::Econazole nitrate::Gyno-pevaryl::Pevaryl::cid_68589
SMILES: Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
InChI Key: InChIKey=LEZWWPYKPKIXLL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cytochrome P450 17A1 (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 325 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Accelrys Curated by ChEMBL | Assay Description In vitro inhibition of human Cytochrome P450 17A1 activity | J Med Chem 46: 2345-51 (2003) Article DOI: 10.1021/jm020576u BindingDB Entry DOI: 10.7270/Q2WD41B7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human recombinant IDO1 using L-tryptophan as substrate after 30 mins by fluorimetric analysis | Bioorg Med Chem 26: 1665-1674 (2018) BindingDB Entry DOI: 10.7270/Q2M61NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 1 (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PCBioAssay | n/a | n/a | 5.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2Q81BGP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA recombination protein RecA (Mycobacterium tuberculosis H37Rv) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2FN14NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA recombination protein RecA (Mycobacterium tuberculosis H37Rv) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DR2SX9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ubiquitin-conjugating enzyme E2 N (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PCBioAssay | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2X34VX0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 144 (CYP144) (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a |
Manchester Interdisciplinary Biocentre | Assay Description Substrate and ligand binding assay using UV- visible absorbance analysis of CYP142 was done on a Cary UV-50 UV-visible scanning spectrophotometer (Va... | J Biol Chem 285: 38270-82 (2010) Article DOI: 10.1074/jbc.M110.164293 BindingDB Entry DOI: 10.7270/Q2251GR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 125 (CYP125) (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a |
Manchester Interdisciplinary Biocentre | Assay Description Substrate and ligand binding assay using UV- visible absorbance analysis of CYP142 was done on a Cary UV-50 UV-visible scanning spectrophotometer (Va... | J Biol Chem 285: 38270-82 (2010) Article DOI: 10.1074/jbc.M110.164293 BindingDB Entry DOI: 10.7270/Q2251GR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 142 (CYP142) (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a |
Manchester Interdisciplinary Biocentre | Assay Description Substrate and ligand binding assay using UV- visible absorbance analysis of CYP142 was done on a Cary UV-50 UV-visible scanning spectrophotometer (Va... | J Biol Chem 285: 38270-82 (2010) Article DOI: 10.1074/jbc.M110.164293 BindingDB Entry DOI: 10.7270/Q2251GR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 130 (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a |
University of California San Francisco | Assay Description Binding assay using CYP130, CYP130 (G234) or CYP142. | J Biol Chem 284: 25211-9 (2009) Article DOI: 10.1074/jbc.M109.017632 BindingDB Entry DOI: 10.7270/Q2RR1WVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 130 (G243A) (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of California San Francisco | Assay Description Binding assay using CYP130, CYP130 (G234) or CYP142. | J Biol Chem 284: 25211-9 (2009) Article DOI: 10.1074/jbc.M109.017632 BindingDB Entry DOI: 10.7270/Q2RR1WVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 142 (CYP142) (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a |
University of California San Francisco | Assay Description Binding assay using CYP130, CYP130 (G234) or CYP142. | J Biol Chem 284: 25211-9 (2009) Article DOI: 10.1074/jbc.M109.017632 BindingDB Entry DOI: 10.7270/Q2RR1WVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Swiss Institute of Bioinformatics Curated by ChEMBL | Assay Description Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLC | Eur J Med Chem 84: 284-301 (2014) Article DOI: 10.1016/j.ejmech.2014.06.078 BindingDB Entry DOI: 10.7270/Q21C1ZJV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 121 (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis H37Rv wild type CYP121 by titration assay | J Med Chem 59: 3272-302 (2016) Article DOI: 10.1021/acs.jmedchem.6b00007 BindingDB Entry DOI: 10.7270/Q2MS3VN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | DrugBank Article PubMed | n/a | n/a | 431 | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Inhibition of CYP3A4 | Eur J Med Chem 44: 2913-22 (2009) Article DOI: 10.1016/j.ejmech.2008.12.004 BindingDB Entry DOI: 10.7270/Q2NC6174 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 51(CYP51) (Mycobacterium tuberculosis) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
Swansea University Curated by ChEMBL | Assay Description Binding affinity to Mycobacterium tuberculosis CYP51 | Antimicrob Agents Chemother 53: 1157-64 (2009) Article DOI: 10.1128/AAC.01237-08 BindingDB Entry DOI: 10.7270/Q22V2GCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malate dehydrogenase cytoplasmic (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Inhibition of malate dehydrogenase (MDH) | J Med Chem 46: 4477-86 (2003) Article DOI: 10.1021/jm030191r BindingDB Entry DOI: 10.7270/Q2X34Z5C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-chymotrypsin (Bos taurus (bovine)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Compound was tested for the inhibition of Chymotrypsinogen | J Med Chem 46: 4477-86 (2003) Article DOI: 10.1021/jm030191r BindingDB Entry DOI: 10.7270/Q2X34Z5C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase AmpC (Escherichia coli) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University Curated by ChEMBL | Assay Description Compound was tested for the inhibition of beta-lactamase | J Med Chem 46: 4477-86 (2003) Article DOI: 10.1021/jm030191r BindingDB Entry DOI: 10.7270/Q2X34Z5C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol 14α-demethylase (CYP51) (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
ACT LLC Curated by ChEMBL | Assay Description Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay | Drug Metab Dispos 35: 493-500 (2007) Article DOI: 10.1124/dmd.106.013888 BindingDB Entry DOI: 10.7270/Q2DF6S2H | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Indoleamine 2,3-dioxygenase 2 (Mus musculus) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom... | Bioorg Med Chem Lett 22: 7641-6 (2012) Article DOI: 10.1016/j.bmcl.2012.10.010 BindingDB Entry DOI: 10.7270/Q20G3M92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Mus musculus) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom... | Bioorg Med Chem Lett 22: 7641-6 (2012) Article DOI: 10.1016/j.bmcl.2012.10.010 BindingDB Entry DOI: 10.7270/Q20G3M92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium release-activated calcium channel (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC... | Bioorg Med Chem 25: 440-449 (2017) Article DOI: 10.1016/j.bmc.2016.11.007 BindingDB Entry DOI: 10.7270/Q2HT2R9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium release-activated calcium channel (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu... | Bioorg Med Chem 25: 440-449 (2017) Article DOI: 10.1016/j.bmc.2016.11.007 BindingDB Entry DOI: 10.7270/Q2HT2R9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile salt export pump (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-... | Hepatology 60: 1015-22 (2014) Article DOI: 10.1002/hep.27206 BindingDB Entry DOI: 10.7270/Q2TF00N2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile salt export pump (Homo sapiens (Human)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... | Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Equus caballus (Horse)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1.74E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2 ... | Bioorg Med Chem 26: 1665-1674 (2018) BindingDB Entry DOI: 10.7270/Q2M61NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 2.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2 m... | Bioorg Med Chem 26: 1665-1674 (2018) BindingDB Entry DOI: 10.7270/Q2M61NVQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme Oxygenase 1 (HO-1) (Rattus norvegicus (rat)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme Oxygenase 2 (HO-2) (Rattus norvegicus (rat)) | BDBM31773![]() (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair |