BDBM318378 US10301317, Example 335::US9624228, Example 335

SMILES CC(c1ccccc1)c1cc2cc3c(n[nH]c3cc2[nH]c1=O)-c1cccnc1C

InChI Key InChIKey=VBABXXLENVCIMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318378   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318378(US10301317, Example 335 | US9624228, Example 335)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318378(US10301317, Example 335 | US9624228, Example 335)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent