BDBM318688 N'-{(3R)-1-[(4S)-7-(3,5- dimethylisoxazol-4-yl)-4-pyridin-2-yl- 4,5-dihydroimidazo[1,5,4- de][1,4]benzoxazin-2-yl]pyrrolidin-3- yl}-N,N-dimethylurea::US10464947, Example 216::US11498926, Example 216::US9624241, Example 216
SMILES CN(C)C(=O)N[C@@H]1CCN(C1)c1nc2ccc(-c3c(C)noc3C)c3OC[C@H](c4ccccn4)n1c23
InChI Key InChIKey=RHKJHWBJIHXHMW-DYESRHJHSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 318688
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Table 12: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Table 11: BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair