BDBM318773 (2S,4S)-4-(2-benzylpiperidin-1-yl)-1-(2,2-diphenylacetyl)-pyrrolidine-2-carboxylic acid::US10370388, Compound 70-A::US9624243, 70-B

SMILES OC(=O)[C@@H]1C[C@@H](CN1C(=O)C(c1ccccc1)c1ccccc1)N1CCCCC1Cc1ccccc1

InChI Key InChIKey=GMIXLHJQCQOBDJ-UWDVWBIHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318773   

TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM318773( (2S,4S)-4-(2-benzylpiperidin-1-yl)-1-(2,2-dipheny...)
Affinity DataIC50:  49.1nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM318773( (2S,4S)-4-(2-benzylpiperidin-1-yl)-1-(2,2-dipheny...)
Affinity DataIC50:  1.34E+3nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent