BindingDB PrimarySearch

BDBM31883 9-cis-retinoic acid (9cRA)::ALL-TRANS-RETINOIC ACID::AT-RA::Atralin::CHEMBL38::MLS000028588::SMR000058245::TRETINOIN::Vitamin A acid::[3H]RA::[3H]Retinoic acid::[3H]Vitamin A acid::[3H]tretinoin::all-trans retinoic acid::cid_444795

SMILES: C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

InChI Key: InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N

Data: 24 KI 49 IC50 67 Kd 98 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 238 hits for monomerid = 31883
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonistic activity of the compound towards retinoic acid receptor-gamma				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards human Retinoic acid receptor alpha				Bioorg Med Chem Lett 7: 2313-2318 (1997) Article DOI: 10.1016/S0960-894X(97)00420-4 BindingDB Entry DOI: 10.7270/Q2Z89CDD
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards cRARbeta2 receptor by displacing 1.1 nM 3[H]-9-cis-RA				Bioorg Med Chem Lett 7: 2313-2318 (1997) Article DOI: 10.1016/S0960-894X(97)00420-4 BindingDB Entry DOI: 10.7270/Q2Z89CDD
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Binding affinity for retinoic acid receptor RAR alpha				Bioorg Med Chem Lett 12: 2447-50 (2002) Article DOI: 10.1016/s0960-894x(02)00427-4 BindingDB Entry DOI: 10.7270/Q29K49JP
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-RA to binding Retinoic acid receptor RAR gamma				Bioorg Med Chem Lett 4: 2117-2122 (1994) Article DOI: 10.1016/S0960-894X(01)80113-X BindingDB Entry DOI: 10.7270/Q2V40V4W
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards cRARbeta2 receptor by displacing 0.82 nM 3[H]-all-trans-RA				Bioorg Med Chem Lett 7: 2313-2318 (1997) Article DOI: 10.1016/S0960-894X(97)00420-4 BindingDB Entry DOI: 10.7270/Q2Z89CDD
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Binding affinity for retinoic acid receptor RAR beta				Bioorg Med Chem Lett 12: 2447-50 (2002) Article DOI: 10.1016/s0960-894x(02)00427-4 BindingDB Entry DOI: 10.7270/Q29K49JP
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards human Retinoic acid receptor gamma				Bioorg Med Chem Lett 7: 2313-2318 (1997) Article DOI: 10.1016/S0960-894X(97)00420-4 BindingDB Entry DOI: 10.7270/Q2Z89CDD
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Binding affinity against Retinoic acid receptor gamma				Bioorg Med Chem Lett 11: 1583-6 (2001) Article DOI: 10.1016/s0960-894x(01)00230-x BindingDB Entry DOI: 10.7270/Q20R9NQW
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Ohio State University Curated by ChEMBL					Assay Description Binding affinity for retinoic acid receptor RAR gamma				Bioorg Med Chem Lett 12: 2447-50 (2002) Article DOI: 10.1016/s0960-894x(02)00427-4 BindingDB Entry DOI: 10.7270/Q29K49JP
The Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIRD GALDERMA Curated by ChEMBL					Assay Description Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligand				J Med Chem 38: 4993-5006 (1996) Article DOI: 10.1021/jm00026a006 BindingDB Entry DOI: 10.7270/Q20G3J8S
CIRD GALDERMA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonistic activity of the compound towards retinoic acid receptor-alpha				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonistic activity of the compound towards retinoic acid receptor-beta				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIRD GALDERMA Curated by ChEMBL					Assay Description Binding affinity to retinoic acid receptor beta using [3H]-CD 367 as radioligand				J Med Chem 38: 4993-5006 (1996) Article DOI: 10.1021/jm00026a006 BindingDB Entry DOI: 10.7270/Q20G3J8S
CIRD GALDERMA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIRD GALDERMA Curated by ChEMBL					Assay Description Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand				J Med Chem 38: 4993-5006 (1996) Article DOI: 10.1021/jm00026a006 BindingDB Entry DOI: 10.7270/Q20G3J8S
CIRD GALDERMA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR beta				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gamma				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonistic activity of the compound towards retinoid X receptor-beta				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonistic activity of the compound towards retinoid X receptor-gamma				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alpha				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	288	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR gamma				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description Agonisticactivity of the compound towards retinoid X receptor-alpha				J Med Chem 40: 4222-34 (1998) Article DOI: 10.1021/jm9704309 BindingDB Entry DOI: 10.7270/Q21J98VC
University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR alpha				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	881	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR beta				J Med Chem 39: 2659-63 (1996) Article DOI: 10.1021/jm960285j BindingDB Entry DOI: 10.7270/Q2988631
Ligand Pharmaceuticals Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic Acid Receptor, gamma (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	n/a	0.200	n/a	n/a	n/a	7.9	4
CNRS					Assay Description Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...				J Mol Biol 302: 155-70 (2000) Article DOI: 10.1006/jmbi.2000.4032 BindingDB Entry DOI: 10.7270/Q2BR8QHR
CNRS					More data for this Ligand-Target Pair
Retinoic Acid Receptor, alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.400	n/a	n/a	n/a	7.9	4
CNRS					Assay Description Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...				J Mol Biol 302: 155-70 (2000) Article DOI: 10.1006/jmbi.2000.4032 BindingDB Entry DOI: 10.7270/Q2BR8QHR
CNRS					More data for this Ligand-Target Pair
Retinoic Acid Receptor, beta (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.400	n/a	n/a	n/a	7.9	4
CNRS					Assay Description Recombinant RAR protein expressed in E. coli was used in the direct binding assay. The apparent dissociation constants (Kd) were determined by the ch...				J Mol Biol 302: 155-70 (2000) Article DOI: 10.1006/jmbi.2000.4032 BindingDB Entry DOI: 10.7270/Q2BR8QHR
CNRS					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	7.0	22
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2F769WQ
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Binding assay using human retinoid X receptor alpha (RXR).				Chem Biol 5: 13-21 (1998) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q289146X
University of Texas Southwestern Medical Center					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	n/a	n/a	3.41E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) Article DOI: 10.1021/bi701954p BindingDB Entry DOI: 10.7270/Q2ZC817P
					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...				PubChem Bioassay (2006) Article DOI: 10.1021/cb300623a BindingDB Entry DOI: 10.7270/Q20863PV
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	n/a	n/a	>9.51E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q25X2795
					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...				PubChem Bioassay (2006) Article DOI: 10.1021/cb400075f BindingDB Entry DOI: 10.7270/Q2VH5M71
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	4.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...				PubChem Bioassay (2006) Article DOI: 10.1111/cbdd.12105 BindingDB Entry DOI: 10.7270/Q2QR4VH9
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Binding assay using human retinoid X receptor alpha (RXR).				Chem Biol 5: 13-21 (1998) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q289146X
University of Texas Southwestern Medical Center					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	7.4	4
University of Texas Southwestern Medical Center					Assay Description Binding assay using human retinoid X receptor alpha (RXR).				Chem Biol 5: 13-21 (1998) Article DOI: 10.1124/jpet.104.066787 BindingDB Entry DOI: 10.7270/Q289146X
University of Texas Southwestern Medical Center					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	n/a	n/a	2.54E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q2251GJ9
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2H70D6B
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...				PubChem Bioassay (2006) Article DOI: 10.1021/cb300729y BindingDB Entry DOI: 10.7270/Q2M043S8
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...				PubChem Bioassay (2007) Article DOI: 10.1021/cc050016r BindingDB Entry DOI: 10.7270/Q2G73C2Z
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by PubChem BioAssay					Assay Description The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2125R2H
University of Pittsburgh Curated by PubChem BioAssay					More data for this Ligand-Target Pair
Retinoic acid receptor alpha/Retinoid X receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor gamma				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/gamma (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was determined for Retinoic acid receptor beta				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transactivation potency of the compound was determined for Retinoic acid receptor beta				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transactivation potency of the compound was determined for Retinoic acid receptor alpha				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor gamma				Bioorg Med Chem Lett 7: 2373-2378 (1997) Article DOI: 10.1016/S0960-894X(97)00435-6 BindingDB Entry DOI: 10.7270/Q2K35TN8
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor gamma using transactivation a...				Bioorg Med Chem Lett 6: 213-218 (1996) Article DOI: 10.1016/0960-894X(95)00588-K BindingDB Entry DOI: 10.7270/Q2BC3ZHZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]-RA as a radioligand in baculovirus expressed receptor				Bioorg Med Chem Lett 6: 213-218 (1996) Article DOI: 10.1016/0960-894X(95)00588-K BindingDB Entry DOI: 10.7270/Q2BC3ZHZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation a...				Bioorg Med Chem Lett 6: 213-218 (1996) Article DOI: 10.1016/0960-894X(95)00588-K BindingDB Entry DOI: 10.7270/Q2BC3ZHZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM31883 (9-cis-retinoic acid (9cRA) \| ALL-TRANS-RETINOIC AC...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Allergan Inc Curated by ChEMBL					Assay Description Effective concentration for retinoic acid receptor RAR alpha transcriptional activation				Bioorg Med Chem Lett 12: 3145-8 (2002) Article DOI: 10.1016/s0960-894x(02)00647-9 BindingDB Entry DOI: 10.7270/Q2WW7H0H
Allergan Inc Curated by ChEMBL					More data for this Ligand-Target Pair

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