BDBM318928 6-(2-(2,2-difluoroethoxy)-3-fluorophenyl)-1-methyl-1H-indazol-3-amine::US10173985, Example 42

SMILES Cn1nc(N)c2ccc(cc12)-c1cccc(F)c1OCC(F)F

InChI Key InChIKey=DHVZAVCXNZMPDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318928   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM318928(6-(2-(2,2-difluoroethoxy)-3-fluorophenyl)-1-methyl...)
Affinity DataIC50:  2.30E+4nMAssay Description:Electrophysiological studies are performed with an IonWorks Quattro (Molecular Devices Corp.) automated patch-clamp electrophysiology platform as des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM318928(6-(2-(2,2-difluoroethoxy)-3-fluorophenyl)-1-methyl...)
Affinity DataIC50:  290nMAssay Description:Electrophysiological studies are performed with an IonWorks Quattro (Molecular Devices Corp.) automated patch-clamp electrophysiology platform as des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent