BDBM319570 1-(((4R,7S)-7-fluoro-6-oxo-5-azaspiro[2.4]heptan-4-yl)methoxy)-7-methoxyisoquinoline-6-carboxamide::US10174000, Example 22

SMILES COc1cc2c(OC[C@@H]3NC(=O)[C@@H](F)C33CC3)nccc2cc1C(N)=O

InChI Key InChIKey=PANBPURSJSQXPA-UONOGXRCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 319570   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319570(1-(((4R,7S)-7-fluoro-6-oxo-5-azaspiro[2.4]heptan-4...)
Affinity DataIC50:  1.70E+3nMAssay Description:This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319570(1-(((4R,7S)-7-fluoro-6-oxo-5-azaspiro[2.4]heptan-4...)
Affinity DataIC50:  2.60E+4nMAssay Description:This is an in vitro assay to measure IRAK4 enzymatic activity utilizing the DELFIA (Dissociation-Enhanced Lanthanide Fluorescent Immunoassay, Perkin-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent