BDBM319735 N-(5-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)ethyl)benzo[d]thiazol-2-yl)acetamide::US10174011, Example 118

SMILES CC(=O)Nc1nc2cc(CCN3CCN(CC3)c3cccc4sccc34)ccc2s1

InChI Key InChIKey=VQLYGEWSCCJRMT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319735   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM319735(N-(5-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)e...)
Affinity DataEC50:  0.602nMAssay Description:The 5-HT1A receptor agonism activity test (The agonism activity of test compounds on 5-HT1A receptor expressing human recombinant 5-HT1A receptor in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM319735(N-(5-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)e...)
Affinity DataIC50:  75nMAssay Description:The 5-HT2A receptor antagonism activity test (The antagonism activity of test compounds on 5-HT2A receptor expressing human recombinant 5-HT2A recept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

US Patent
LigandPNGBDBM319735(N-(5-(2-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)e...)
Affinity DataIC50:  119nMAssay Description:The D2 receptor antagonism activity test (The antagonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent