BDBM319818 US10174015, Compound 31

SMILES Oc1ccc(CCCCCC(=O)N2CCOC2=O)cc1

InChI Key InChIKey=DHWUVTVUAVGPBO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 319818   

TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Xiamen University

US Patent
LigandPNGBDBM319818(US10174015, Compound 31)
Affinity DataIC50:  90nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM319818(US10174015, Compound 31)
Affinity DataIC50:  61nMAssay Description:Inhibition of rat NAAA expressed in HEK293 cells using heptadecenoylethanolamide as substrate after 30 mins by HPLC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM319818(US10174015, Compound 31)
Affinity DataIC50:  61nMAssay Description:Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Xiamen University

US Patent
LigandPNGBDBM319818(US10174015, Compound 31)
Affinity DataIC50:  260nMAssay Description:In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent