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BDBM320376 2-(1-hydroxyethyl)-1H- pyrrolo[3,2-b]pyridine-7- carboxylic acid::US10174026, Example 18

SMILES: CC(O)c1cc2nccc(C(O)=O)c2[nH]1

InChI Key: InChIKey=RMCMBFPHTFWEBT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320376   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5A


(Homo sapiens (Human))
BDBM320376
PNG
(2-(1-hydroxyethyl)-1H- pyrrolo[3,2-b]pyridine-7- c...)
Show SMILES CC(O)c1cc2nccc(C(O)=O)c2[nH]1
Show InChI InChI=1S/C10H10N2O3/c1-5(13)7-4-8-9(12-7)6(10(14)15)2-3-11-8/h2-5,12-13H,1H3,(H,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...


US Patent US10174026 (2019)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM320376
PNG
(2-(1-hydroxyethyl)-1H- pyrrolo[3,2-b]pyridine-7- c...)
Show SMILES CC(O)c1cc2nccc(C(O)=O)c2[nH]1
Show InChI InChI=1S/C10H10N2O3/c1-5(13)7-4-8-9(12-7)6(10(14)15)2-3-11-8/h2-5,12-13H,1H3,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10174026 (2019)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))
BDBM320376
PNG
(2-(1-hydroxyethyl)-1H- pyrrolo[3,2-b]pyridine-7- c...)
Show SMILES CC(O)c1cc2nccc(C(O)=O)c2[nH]1
Show InChI InChI=1S/C10H10N2O3/c1-5(13)7-4-8-9(12-7)6(10(14)15)2-3-11-8/h2-5,12-13H,1H3,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...


US Patent US10174026 (2019)

More data for this
Ligand-Target Pair