BDBM320447 2-(4-chloro-3-methoxybenzyl)- 1H-pyrrolo[3,2-b]pyridine-7- carboxylic acid::US10174026, Example 128::US9738637, Example 128

SMILES COc1cc(Cc2cc3nccc(C(O)=O)c3[nH]2)ccc1Cl

InChI Key InChIKey=UZSUVCSIXHHZRS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 320447   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320447(2-(4-chloro-3-methoxybenzyl)- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50:  5.50E+3nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320447(2-(4-chloro-3-methoxybenzyl)- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320447(2-(4-chloro-3-methoxybenzyl)- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quantical Research

US Patent
LigandPNGBDBM320447(2-(4-chloro-3-methoxybenzyl)- 1H-pyrrolo[3,2-b]pyr...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent