BDBM320554 US10174035, Compound 97::[4-(Dimethylamino)piperidin-1-yl][5-(1,3-dimethyl-1H-pyrazol-4-yl)-6-fluoro-7-(morpholin-4-yl)-3H-imidazo[4,5-b]pyridin-2-yl]methanone

SMILES CN(C)C1CCN(CC1)C(=O)c1nc2c(N3CCOCC3)c(F)c(nc2[nH]1)-c1cn(C)nc1C

InChI Key InChIKey=RGSQXODTSAFNLI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 320554   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM320554(US10174035, Compound 97 | [4-(Dimethylamino)piperi...)
Affinity DataIC50:  1.08E+3nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM320554(US10174035, Compound 97 | [4-(Dimethylamino)piperi...)
Affinity DataIC50: >1.00E+4nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM320554(US10174035, Compound 97 | [4-(Dimethylamino)piperi...)
Affinity DataIC50:  3nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM320554(US10174035, Compound 97 | [4-(Dimethylamino)piperi...)
Affinity DataIC50:  3nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM320554(US10174035, Compound 97 | [4-(Dimethylamino)piperi...)
Affinity DataIC50:  961nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent