BDBM321027 4-[4-[2-[4-amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamoylamino)methyl]cyclopentyl]pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl]-3,5-difluoro-phenyl]morpholine::US10174040, Example 101

SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CCOCC3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=LPKUQJQPLBLCCF-GYHJHTCASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321027   

TargetNEDD8-conjugating enzyme UBE2F(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321027(4-[4-[2-[4-amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-...)
Affinity DataIC50:  7.60nMAssay Description:A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent