BDBM321072 8-((2-amino-5,5,5-trifluoropentyl)oxy)-5,9-dimethylbenzo[c][1,7]naphthyridin-6(5H)-one::US10174044, Example 6

SMILES [#6]C([#6])([#6])[#8]-[#6](=O)-[#6](-[#6]-[#6]C(F)(F)F)\[#7]=[#6](\c1ccccc1)-c1ccccc1

InChI Key InChIKey=XVSQOLAOMZHRGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321072   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321072(8-((2-amino-5,5,5-trifluoropentyl)oxy)-5,9-dimethy...)
Affinity DataIC50:  3.70nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent